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Nobuo Hirotsu Selected Research

Infections

1/2022Comparing the cobas Influenza A/B Nucleic acid test for use on the cobas Liat System (Liat) with rapid antigen tests for clinical management of Japanese patients at the point of care.
1/2021Efficacy and safety of baloxavir marboxil versus neuraminidase inhibitors in the treatment of influenza virus infection in high-risk and uncomplicated patients - a Bayesian network meta-analysis.
1/2020Baloxavir Marboxil in Japanese Pediatric Patients With Influenza: Safety and Clinical and Virologic Outcomes.
1/2019The effect of neuraminidase inhibitors on household transmission in Japanese patients with influenza A and B infection: A prospective, observational study.
1/2019Antibody dynamics in Japanese paediatric patients with influenza A infection treated with neuraminidase inhibitors in a randomised trial.
1/2018Clinical and virologic effects of four neuraminidase inhibitors in influenza A virus-infected children (aged 4-12 years): an open-label, randomized study in Japan.
11/2011Phase III randomized, double-blind study comparing single-dose intravenous peramivir with oral oseltamivir in patients with seasonal influenza virus infection.
12/2009Clinical effectiveness of oseltamivir and zanamivir for treatment of influenza A virus subtype H1N1 with the H274Y mutation: a Japanese, multicenter study of the 2007-2008 and 2008-2009 influenza seasons.
1/2008A comparison of the effectiveness of zanamivir and oseltamivir for the treatment of influenza A and B.

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Nobuo Hirotsu Research Topics

Disease

30Human Influenza (Influenza)
01/2023 - 06/2003
10Fever (Fevers)
01/2023 - 05/2005
9Infections
01/2022 - 01/2008
3Herpesviridae Infections (Herpesvirus Infection)
01/2018 - 06/2011
1COVID-19
01/2023
1Pneumonia (Pneumonitis)
01/2021
1Coinfection
01/2019
1Reinfection
01/2013
1Drug-Related Side Effects and Adverse Reactions
11/2011
1Respiratory Tract Diseases (Respiratory Tract Disease)
06/2011
1Vomiting
09/2010
1Virus Diseases (Viral Diseases)
09/2009

Drug/Important Bio-Agent (IBA)

16Oseltamivir (Tamiflu)FDA Link
01/2019 - 06/2003
11Neuraminidase (Sialidase)IBA
10/2021 - 09/2009
9Antiviral Agents (Antivirals)IBA
01/2022 - 11/2011
9Zanamivir (Relenza)FDA Link
01/2019 - 06/2007
8baloxavirIBA
02/2021 - 01/2018
5AntigensIBA
01/2022 - 05/2005
5laninamivirIBA
02/2021 - 05/2013
5peramivirIBA
01/2019 - 09/2010
2Proteins (Proteins, Gene)FDA Link
01/2023 - 01/2020
2EndonucleasesIBA
01/2019 - 01/2018
1Messenger RNA (mRNA)IBA
01/2023
1RNA (Ribonucleic Acid)IBA
01/2023
1Nucleic AcidsIBA
01/2022
1VaccinesIBA
01/2019
1Complement System Proteins (Complement)IBA
01/2019
1C-Reactive ProteinIBA
01/2014
1Immunoglobulin G (IgG)IBA
01/2013
1Immunologic Factors (Immunomodulators)IBA
01/2013
1Clarithromycin (Biaxin)FDA LinkGeneric
01/2013
1Immunoglobulin A (IgA)IBA
01/2013
1benzmetanide (H 25)IBA
08/2006
1Indicators and Reagents (Reagents)IBA
05/2005
1Amantadine (Aman)FDA LinkGeneric
05/2005

Therapy/Procedure

7Therapeutics
04/2012 - 08/2006
1Aftercare (After-Treatment)
04/2012
1Oral Administration
11/2011
1Intravenous Infusions
11/2011
1Intravenous Administration
09/2010